Strength & MobilityModerate evidenceInjury Reduction & Tendon Health

Balance training reduces ankle sprains by about a third in sporting populations, with the clearest benefit in people who have sprained an ankle before

Interpretation

A meta-analysis of 7 RCTs (3,726 participants) found risk ratio 0.65 overall and 0.64 in people with a previous sprain; the primary-prevention estimate (0.57) rests on two non-significant trials (Schiftan 2015). An 8-week unsupervised home programme cut recurrences from 33% to 22% in 522 athletes aged 12-70 with a near-even sex split (Hupperets 2009), and a cluster RCT in 765 high-school athletes found 6.1% vs 9.9% sprains with no significant effect in those without previous sprain (McGuine 2006). An overview of 46 reviews rates neuromuscular training moderate and bracing strong for preventing recurrence (Doherty 2017; Vuurberg 2018). Graded moderate rather than strong because the trials are mostly team sports; no trial has tested runners or triathletes, and trail-running sprain rates are poorly measured (Viljoen 2021).

Practical implication

Triathletes with a previous ankle sprain, especially one never rehabilitated, should add a few minutes of progressive single-leg balance work several times a week, for at least 8 weeks, before and during winter trail running, and consider a brace if sprains recur. For people who have never sprained an ankle the benefit is unproven. Extrapolated from team-sport trials, not runners.

Sources

7 sources, independently verified.

Meta-analysisIndependently verified
The effectiveness of proprioceptive training in preventing ankle sprains in sporting populations: a systematic review and meta-analysis ↗
Schiftan GS, Ross LA, Hahne AJ · 2015 · Journal of Science and Medicine in Sport

7 RCTs, 3,726 sporting participants. Proprioceptive (balance) training reduced ankle sprains: risk ratio 0.65 (95% CI 0.55-0.77) overall, 0.64 (0.51-0.81) in people with a previous sprain, and 0.57 (0.34-0.97) without, the last from two individually non-significant trials, so primary prevention is inconclusive. Mostly team sports.

Peer-reviewed studyRCTIndependently verified
Effect of unsupervised home based proprioceptive training on recurrences of ankle sprain: randomised controlled trial ↗
Hupperets MDW, Verhagen EALM, van Mechelen W · 2009 · BMJ
522 athletes aged 12-70 with a lateral ankle sprain in the previous 2 months (248 F, 274 M)

Usual care plus an 8-week unsupervised home proprioceptive programme vs usual care; 1-year follow-up. Recurrence 22% vs 33% (RR 0.63, 95% CI 0.45-0.88; 35% reduction; NNT 9); time-loss and cost-incurring sprains also reduced. Benefit significant only in athletes whose original sprain was not medically treated.

Peer-reviewed studyRCTIndependently verified
The effect of a balance training program on the risk of ankle sprains in high school athletes ↗
McGuine TA, Keene JS · 2006 · American Journal of Sports Medicine
765 high-school soccer and basketball players (523 F, 242 M), 55 teams, cluster-randomised

Sprains 6.1% with balance training vs 9.9% in controls (1.13 vs 1.87 per 1000 exposures, P = .04). Previous sprain roughly doubled risk. In athletes without a previous sprain, 4.3% vs 7.7% was not significant (P = .059). Adolescent team-sport athletes.

Systematic reviewIndependently verified
Treatment and prevention of acute and recurrent ankle sprain: an overview of systematic reviews with meta-analysis ↗
Doherty C, Bleakley C, Delahunt E, Holden S · 2017 · British Journal of Sports Medicine

Overview of 46 systematic reviews (mean AMSTAR 6.5/11). Acute sprain: strong evidence for NSAIDs and early mobilisation, moderate for exercise and manual therapy, conflicting for surgery and acupuncture, insufficient for ultrasound. Preventing recurrence: strong evidence for bracing, moderate for neuromuscular training.

Expert consensusIndependently verified
Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline ↗
Vuurberg G, Hoorntje A, Wink LM, van der Doelen BFW, van den Bekerom MPJ, Dekker R, van Dijk CN, Krips R, Loogman MCM, Ridderikhof ML, Smithuis FF, Stufkens SAS, Verhagen EALM, de Bie RA, Kerkhoffs GMMJ · 2018 · British Journal of Sports Medicine

Delayed physical examination at 4-5 days most reliably assesses severity; a short immobilisation may relieve pain and swelling; tape or brace with an exercise programme best for acute ligament rupture; supervised exercise-based programmes preferred over passive modalities; NSAIDs used with caution as they may suppress healing; braces effective for preventing recurrent sprains.

Expert consensusIndependently verified
Evidence review for the 2016 International Ankle Consortium consensus statement on the prevalence, impact and long-term consequences of lateral ankle sprains ↗
Gribble PA, Bleakley CM, Caulfield BM, Docherty CL, Fourchet F, Fong DT · 2016 · British Journal of Sports Medicine

Lateral ankle sprains are the most common musculoskeletal injury in physically active people; recurrence is high and many develop chronic ankle instability, linked to reduced physical activity, lower quality of life and post-traumatic ankle osteoarthritis. Abstract gives no figures.

Systematic reviewIndependently verified
Epidemiology of injury and illness among trail runners: a systematic review ↗
Viljoen CT, Janse van Rensburg DC, Verhagen E, van Mechelen W, Tomas R, Schoeman M, Scheepers S, Korkie E · 2021 · Sports Medicine

16 studies, 8,644 trail runners, mostly single-day races. Injury incidence 1.6-4,285.0 per 1000 h. Foot was the most common injury location, then knee, lower leg, thigh and ankle; skin injuries most common type, with ligament sprains among listed types.